Liraglutide and calcitonin

Calcitonin and calcitonin receptors Mini - review

Calcitonin (CT) is a polypeptide hormone with 32 aminoacids syntetized primarily by the thyroid. Several evidences support the existence of nonthyroidal CT like peptide. The CT gene transcript also encodes a distinct peptide known as calcitonin gene related peptide (CGRP) which is a potent vasodilator and responsible for the stimulation of the glomerular filtration rate. In addition, a 37 amino...

Liraglutide (Victoza)

498 P&T® • September 2010 • Vol. 35 No. 9 INTRODUCTION According to the Centers for Disease Control and Prevention (CDC) prevalence data for 2007, diabetes is a chronic and progressive disease that af fects nearly 24 million people in the U.S.1 It is projected that by the year 2030, more than 30 million people will have diabetes.2 From 90% to 95% of diagnosed cases are type-2 diabetes, which is...

Liraglutide-induced autoimmune hepatitis.

IMPORTANCE Use of incretin-based hypoglycemic agents is increasing, but safety data remain limited. We treated a woman with marker-negative autoimmune hepatitis associated with the glucagon-like peptide 1 agonist liraglutide. OBSERVATIONS A young woman with type 2 diabetes mellitus and vitiligo presented with a 10-day history of acute hepatitis. Other than starting liraglutide therapy 4 month...

Liraglutide-induced acute pancreatitis.

An obese lady of 51 year with Type 2 Diabetes Mellitus for 13 years was prescribed Liraglutide, a glucagon like peptide (GLP-1) analogue (Victoza) for glycaemic control and reduction of weight. She was on gliclazide and Insulin prior to initiation of Liraglutide. Eight weeks after initiation of GLP -1 analogue, she developed severe abdominal pain, nausea and vomiting. She was admitted to a priv...

Victoza; INN-Liraglutide